Oleuropein inhibits invasion of squamous cell carcinoma of the head and neck through TGF-β1 signaling pathway

Oleuropein inhibits invasion of squamous cell carcinoma of the head and neck through TGF-β1 signaling pathway

Abstract Background Squamous cell carcinoma of the head and neck (SCCHN) is globally the sixth most common cancer. TGF-β1 is a key regulator of cell proliferation and differentiation, and it induces the epithelial-mesenchymal transition (EMT) by activating Smad2 signaling in SCCHN cells. Previous st...

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Bibliographic Details
Main Authors: Ting Xu, Xuan Liu
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Cancer
Subjects:
Oleuropein
SCCHN
Epithelial-mesenchymal transition
TGF-β1
Metastasis
Online Access:https://doi.org/10.1186/s12885-022-09979-2

Internet

https://doi.org/10.1186/s12885-022-09979-2

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