Extracellular matrix abnormalities in the hippocampus of subjects with substance use disorder

Abstract Contextual triggers are significant factors contributing to relapse in substance use disorders (SUD). Emerging evidence points to a critical role of extracellular matrix (ECM) molecules as mediators of reward memories. Chondroitin sulfate proteoglycans (CSPGs) are a subset of ECM molecules...

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Bibliographic Details
Main Authors: Jake Valeri, Charlotte Stiplosek, Sinead M. O’Donovan, David Sinclair, Kathleen A. Grant, Ratna Bollavarapu, Donna M. Platt, Craig A. Stockmeier, Barbara Gisabella, Harry Pantazopoulos
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-02833-y