Accurate prediction of secreted substrates and identification of a conserved putative secretion signal for type III secretion systems.
The type III secretion system is an essential component for virulence in many Gram-negative bacteria. Though components of the secretion system apparatus are conserved, its substrates--effector proteins--are not. We have used a novel computational approach to confidently identify new secreted effect...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-04-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2668754?pdf=render |