Molecular mechanisms involved in the IL-6-mediated upregulation of indoleamine 2,3-dioxygenase 1 (IDO1) expression in the chorionic villi and decidua of women in early pregnancy
Abstract Background IL-6 induces the upregulation of indoleamine 2,3-dioxygenase (IDO1) at the maternal-foetal interface, but the regulation mechanisms of IDO1 by IL-6 at this interface have not been fully understood. Methods Western blotting, qRT–PCR and/or immunohistochemistry were employed to mea...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | BMC Pregnancy and Childbirth |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12884-022-05307-5 |