Network Analysis Reveals the Recognition Mechanism for Dimer Formation of Bulb-type Lectins

Abstract The bulb-type lectins are proteins consist of three sequential beta-sheet subdomains that bind to specific carbohydrates to perform certain biological functions. The active states of most bulb-type lectins are dimeric and it is thus important to elucidate the short- and long-range recogniti...

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Bibliographic Details
Main Authors: Yunjie Zhao, Yiren Jian, Zhichao Liu, Hang Liu, Qin Liu, Chanyou Chen, Zhangyong Li, Lu Wang, H. Howie Huang, Chen Zeng
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03003-5