IMMUNE SENESCENCE-RELATED GENE EXPRESSION PROFILE IN CD4+ T-LYMPHOCYTES OF HTLV-1 ASYMPTOMATIC CARRIERS AND PATIENTS WITH ADULT T-CELL LEUKEMIA/LYMPHOMA (ATLL): A BRAZILIAN PRELIMINARY STUDY

Introduction: ATLL is a rare and aggressive neoplasm caused by the human T-lymphotropic virus type 1 (HTLV-1). It is estimated that at least 5-10 million people carry HTLV-1 and 2-5% out of them will develop ATLL. Our group demonstrated an increase of cells in G0/G1 phase of cell cycle and aneuploid...

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Bibliographic Details
Main Authors: JRA Filho, HF Culler, D Levy, KS Oliveira, D Nogueira, LV Almeida, V Rocha, Y Nukui, LAPC Lage, J Pereira
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137921002704