Flotillin scaffold activity contributes to type VII secretion system assembly in Staphylococcus aureus.

Scaffold proteins are ubiquitous chaperones that promote efficient interactions between partners of multi-enzymatic protein complexes; although they are well studied in eukaryotes, their role in prokaryotic systems is poorly understood. Bacterial membranes have functional membrane microdomains (FMM)...

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Bibliographic Details
Main Authors: Benjamin Mielich-Süss, Rabea M Wagner, Nicole Mietrach, Tobias Hertlein, Gabriella Marincola, Knut Ohlsen, Sebastian Geibel, Daniel Lopez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006728