Phenome-wide Mendelian randomisation analysis of 378,142 cases reveals risk factors for eight common cancers

Phenome-wide Mendelian randomisation analysis of 378,142 cases reveals risk factors for eight common cancers

Abstract For many cancers there are only a few well-established risk factors. Here, we use summary data from genome-wide association studies (GWAS) in a Mendelian randomisation (MR) phenome-wide association study (PheWAS) to identify potentially causal relationships for over 3,000 traits. Our outcom...

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Bibliographic Details
Main Authors: Molly Went, Amit Sud, Charlie Mills, Abi Hyde, Richard Culliford, Philip Law, Jayaram Vijayakrishnan, Ines Gockel, Carlo Maj, Johannes Schumacher, Claire Palles, Martin Kaiser, Richard Houlston
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46927-z

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https://doi.org/10.1038/s41467-024-46927-z

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