Integrative analysis of summary data from GWAS and eQTL studies implicates genes differentially expressed in Alzheimer’s disease
Abstract Background Although genome-wide association studies (GWAS) have successfully located various genetic variants susceptible to Alzheimer’s Disease (AD), it is still unclear how specific variants interact with genes and tissues to elucidate pathologies associated with AD. Summary-data-based Me...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-06-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12864-022-08584-8 |