s-Triazine Derivatives Functionalized with Alkylating 2-Chloroethylamine Fragments as Promising Antimicrobial Agents: Inhibition of Bacterial DNA Gyrases, Molecular Docking Studies, and Antibacterial and Antifungal Activity

s-Triazine Derivatives Functionalized with Alkylating 2-Chloroethylamine Fragments as Promising Antimicrobial Agents: Inhibition of Bacterial DNA Gyrases, Molecular Docking Studies, and Antibacterial and Antifungal Activity

The spectrum of biological properties of s-triazine derivatives is broad and includes anti-microbial, anti-cancer, and anti-neurodegenerative activities, among others. The s-triazine molecule, due to the possibility of substituting three substituents, offers many opportunities to obtain hybrid compo...

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Bibliographic Details
Main Authors: Dawid Maliszewski, Rasime Demirel, Agnieszka Wróbel, Maciej Baradyn, Artur Ratkiewicz, Danuta Drozdowska
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceuticals
Subjects:
triazine scaffold
antibacterial agent
antifungal agent
DNA gyrase
alkylating agents
Online Access:https://www.mdpi.com/1424-8247/16/9/1248

Internet

https://www.mdpi.com/1424-8247/16/9/1248

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