The Fungicidal Action of Micafungin is Independent on Both Oxidative Stress Generation and HOG Pathway Signaling in <i>Candida albicans</i>

The Fungicidal Action of Micafungin is Independent on Both Oxidative Stress Generation and HOG Pathway Signaling in <i>Candida albicans</i>

In fungi, the Mitogen-Activated Protein kinase (MAPK) pathways sense a wide variety of environmental stimuli, leading to cell adaptation and survival. The HOG pathway plays an essential role in the pathobiology of <i>Candida albicans</i>, including the colonization of the gastrointestina...

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Bibliographic Details
Main Authors: Rebeca Alonso-Monge, José P. Guirao-Abad, Ruth Sánchez-Fresneda, Jesús Pla, Genoveva Yagüe, Juan Carlos Argüelles
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Microorganisms
Subjects:
HOG pathway
antifungals
amphotericin B (AMB), micafungin (MF), MAPK phosphorylation
ROS
<i>Candida albicans</i>
Online Access:https://www.mdpi.com/2076-2607/8/12/1867

Internet

https://www.mdpi.com/2076-2607/8/12/1867

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