Resatorvid alleviates experimental inflammatory TMJOA by restraining chondrocyte pyroptosis and synovial inflammation

Resatorvid alleviates experimental inflammatory TMJOA by restraining chondrocyte pyroptosis and synovial inflammation

Abstract Objectives Innate immunity plays a significant role in the pathogenesis of temporomandibular joint osteoarthritis (TMJOA), which is characterized by synovial inflammation and condylar cartilage degradation. We are urged to investigate the impact of Resatorvid, a preventative drug that inhib...

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Bibliographic Details
Main Authors: Xin Liu, Huimin Li, Yaping Feng, Huilin Guo, Yingjie Li, Jin Ke, Xing Long
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Arthritis Research & Therapy
Subjects:
TMJOA
Resatorvid
Chondrocyte pyroptosis
Macrophage inflammation
NLRP3
ROS
Online Access:https://doi.org/10.1186/s13075-023-03214-4

Internet

https://doi.org/10.1186/s13075-023-03214-4

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