The role of endothelial TRP channels in age-related vascular cognitive impairment and dementia

Transient receptor potential (TRP) proteins are part of a superfamily of polymodal cation channels that can be activated by mechanical, physical, and chemical stimuli. In the vascular endothelium, TRP channels regulate two fundamental parameters: the membrane potential and the intracellular Ca2+ con...

Full description

Bibliographic Details
Main Authors: Sharon Negri, Madison Sanford, Helen Shi, Stefano Tarantini
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1149820/full