Exploring the Potential of Lapatinib, Fulvestrant, and Paclitaxel Conjugated with Glycidylated PAMAM G4 Dendrimers for Cancer and Parasite Treatment

Exploring the Potential of Lapatinib, Fulvestrant, and Paclitaxel Conjugated with Glycidylated PAMAM G4 Dendrimers for Cancer and Parasite Treatment

Fulvestrant (F), lapatinib (L), and paclitaxel (P) are hydrophobic, anticancer drugs used in the treatment of estrogen receptor (ER) and epidermal growth factor receptor (EGFR)-positive breast cancer. In this study, glycidylated PAMAM G4 dendrimers, substituted with F, L, and/or P and targeting tumo...

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Bibliographic Details
Main Authors: Łukasz Uram, Konrad Wróbel, Małgorzata Walczak, Żaneta Szymaszek, Magdalena Twardowska, Stanisław Wołowiec
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
paclitaxel
fulvestrant
lapatinib
glycidylated PAMAM G4 dendrimer
U-118 MG glioma
A549 NSCLC
Online Access:https://www.mdpi.com/1420-3049/28/17/6334

Internet

https://www.mdpi.com/1420-3049/28/17/6334

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