Evidence for Epistatic Interaction between <i>HLA-G</i> and <i>LILRB1</i> in the Pathogenesis of Nonsegmental Vitiligo

Evidence for Epistatic Interaction between <i>HLA-G</i> and <i>LILRB1</i> in the Pathogenesis of Nonsegmental Vitiligo

Vitiligo is the most frequent cause of depigmentation worldwide. Genetic association studies have discovered about 50 loci associated with disease, many with immunological functions. Among them is HLA-G, which modulates immunity by interacting with specific inhibitory receptors, mainly LILRB1 and LI...

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Bibliographic Details
Main Authors: Maria Luiza de Oliveira-Caramez, Luciana Veiga-Castelli, Andreia S. Souza, Renata Nahas Cardili, David Courtin, Milena Flória-Santos, Eduardo Donadi, Silvana Giuliatti, Audrey Sabbagh, Erick C. Castelli, Celso Teixeira Mendes-Junior
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
ancestry
Brazil
ILT-2
ILT-4
LILRB2
SNP<i>for</i>ID
Online Access:https://www.mdpi.com/2073-4409/12/4/630

Internet

https://www.mdpi.com/2073-4409/12/4/630

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