Mutations in the acetylation hotspots of Rbl2 are associated with increased risk of breast cancer.

Retinoblastoma like protein-2 (Rbl2) is functionally regulated by phosphorylation and acetylation. Previously, we demonstrated that lysine K1083 (K1079 in human Rbl2) is a potential target for acetylation but its functional role remains elusive. We investigated alterations in human Rbl2 gene specifi...

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Bibliographic Details
Main Authors: Farman Ullah, Nadia Khurshid, Qaiser Fatimi, Peter Loidl, Muhammad Saeed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0266196