Exosomal miR-105-5p derived from bladder cancer stem cells targets for GPR12 to promote the malignancy of bladder cancer

Abstract Bladder cancer stem cells (BCSCs) are considered as the root cause of BC initiation and recurrence, and exosomes derived from BCSCs (CSCs-exo) are the vital tool for establishing a stable tumor microenvironment. miR-105-5p has been revealed to promote tumor growth in a variety of cancers, b...

Full description

Bibliographic Details
Main Authors: Gaojian Pan, Bo Jiang, Zhongquan Yi, Jiuhu Yin, Yadong Liu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Urology
Subjects:
Online Access:https://doi.org/10.1186/s12894-023-01326-2