A unifying model for the propagation of prion proteins in yeast brings insight into the [PSI+] prion.

The use of yeast systems to study the propagation of prions and amyloids has emerged as a crucial aspect of the global endeavor to understand those mechanisms. Yeast prion systems are intrinsically multi-scale: the molecular chemical processes are indeed coupled to the cellular processes of cell gro...

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Bibliographic Details
Main Authors: Paul Lemarre, Laurent Pujo-Menjouet, Suzanne S Sindi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007647