Whole genome amplification and de novo assembly of single bacterial cells.

Whole genome amplification and de novo assembly of single bacterial cells.

Single-cell genome sequencing has the potential to allow the in-depth exploration of the vast genetic diversity found in uncultured microbes. We used the marine cyanobacterium Prochlorococcus as a model system for addressing important challenges facing high-throughput whole genome amplification (WGA...

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Bibliographic Details
Main Authors: Sébastien Rodrigue, Rex R Malmstrom, Aaron M Berlin, Bruce W Birren, Matthew R Henn, Sallie W Chisholm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2731171?pdf=render

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http://europepmc.org/articles/PMC2731171?pdf=render

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