Barrier disrupting effects of alternaria alternata extract on bronchial epithelium from asthmatic donors.

Barrier disrupting effects of alternaria alternata extract on bronchial epithelium from asthmatic donors.

Sensitization and exposure to the allergenic fungus Alternaria alternata has been associated with increased risk of asthma and asthma exacerbations. The first cells to encounter inhaled allergens are epithelial cells at the airway mucosal surface. Epithelial barrier function has previously been repo...

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Bibliographic Details
Main Authors: Marina S Leino, Matthew Loxham, Cornelia Blume, Emily J Swindle, Nivenka P Jayasekera, Patrick W Dennison, Betty W H Shamji, Matthew J Edwards, Stephen T Holgate, Peter H Howarth, Donna E Davies
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3751915?pdf=render

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http://europepmc.org/articles/PMC3751915?pdf=render

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