Protective effect of bone marrow mesenchymal stem cell-derived exosomes on cardiomyoblast hypoxia-reperfusion injury through the HAND2-AS1/miR-17-5p/Mfn2 axis

Protective effect of bone marrow mesenchymal stem cell-derived exosomes on cardiomyoblast hypoxia-reperfusion injury through the HAND2-AS1/miR-17-5p/Mfn2 axis

Abstract Background The exosomes (exos) of bone marrow mesenchymal stem cells (BMSCs) play an important therapeutic role in repairing myocardial injury. The purpose of this study was to explore how the exos of BMSCs can alleviate the myocardial cell injury caused by hypoxia/reoxygenation (H/R) throu...

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Bibliographic Details
Main Authors: Qiang Li, Yanling Bu, Haifeng Shao, Wenhua Li, Di Zhao, Jian Wang
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Cardiovascular Disorders
Subjects:
Exosome
HAND2-AS1/miR-17-5p/Mfn2
H/R damage
Oxidative stress
Inflammation
Online Access:https://doi.org/10.1186/s12872-023-03148-4

Internet

https://doi.org/10.1186/s12872-023-03148-4

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