Myostatin/Activin-A Signaling in the Vessel Wall and Vascular Calcification

Myostatin/Activin-A Signaling in the Vessel Wall and Vascular Calcification

A current hypothesis is that transforming growth factor-β signaling ligands, such as activin-A and myostatin, play a role in vascular damage in atherosclerosis and chronic kidney disease (CKD). Myostatin and activin-A bind with different affinity the activin receptors (type I or II), activating dist...

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Bibliographic Details
Main Authors: Pasquale Esposito, Daniela Verzola, Daniela Picciotto, Leda Cipriani, Francesca Viazzi, Giacomo Garibotto
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
myostatin
activin A
activin receptors
atherosclerosis
vascular calcification
CKD-MBD
Online Access:https://www.mdpi.com/2073-4409/10/8/2070

Internet

https://www.mdpi.com/2073-4409/10/8/2070

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