The enigma of RIPK1 in the liver: More than just a kinase

Receptor interacting protein kinase 1 (RIPK1) represents a key molecule in cell death. Here, we discuss our recent data on RIPK1 in liver injury and hepatocellular carcinoma development and put these into relation to previous experimental findings to underpin that it exerts opposing kinase-dependent...

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Bibliographic Details
Main Authors: Mihael Vucur, Anne T. Schneider, Jérémie Gautheron, Tom Luedde
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2017.1304191