The Impairment of Cell Metabolism by Cardiovascular Toxicity of Doxorubicin Is Reversed by Bergamot Polyphenolic Fraction Treatment in Endothelial Cells

The Impairment of Cell Metabolism by Cardiovascular Toxicity of Doxorubicin Is Reversed by Bergamot Polyphenolic Fraction Treatment in Endothelial Cells

The beneficial effects of bergamot polyphenolic fraction (BPF) on the mitochondrial bioenergetics of porcine aortic endothelial cells (pAECs) were verified under the cardiotoxic action of doxorubicin (DOX). The cell viability of pAECs treated for 24 h with different concentrations of DOX was reduced...

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Bibliographic Details
Main Authors: Cristina Algieri, Chiara Bernardini, Francesca Oppedisano, Debora La Mantia, Fabiana Trombetti, Ernesto Palma, Monica Forni, Vincenzo Mollace, Giovanni Romeo, Ilaria Troisio, Salvatore Nesci
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
cell metabolism
bergamot polyphenolic fraction
doxorubicin
mitochondria
porcine aortica endothelial cells
Online Access:https://www.mdpi.com/1422-0067/23/16/8977

Internet

https://www.mdpi.com/1422-0067/23/16/8977

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