Decoding lifespan secrets: the role of the gonad in Caenorhabditis elegans aging

The gonad has become a central organ for understanding aging in C. elegans, as removing the proliferating stem cells in the germline results in significant lifespan extension. Similarly, when starvation in late larval stages leads to the quiescence of germline stem cells the adult nematode enters re...

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Bibliographic Details
Main Authors: Andre Pires da Silva, Rhianne Kelleher, Luke Reynoldson
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2024.1380016/full