Metabolomic Assay, Computational Screening, and Pharmacological Evaluation of Caulerpa racemosa as an Anti-obesity With Anti-aging by Altering Lipid Profile and Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-α Levels

Obesity is associated with an accelerated aging process, which prevents healthy aging. Both obesity and aging were manifested in the peroxisome proliferator-activated receptor-γ coactivator α (PGC-1α) level. These studies fulfill the scientific gap in assembled pharmacological activity assay of Caul...

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Main Authors: Happy Kurnia Permatasari, Fahrul Nurkolis, Hardinsyah Hardinsyah, Nurpudji Astuti Taslim, Nindy Sabrina, Faisal Maulana Ibrahim, Jodi Visnu, Dian Aruni Kumalawati, Sri Awalia Febriana, Toto Sudargo, Melvin Junior Tanner, Isma Kurniatanty, Vincentius Mario Yusuf, Ronald Rompies, Muhammad Rahimi Bahar, Holipah Holipah, Nelly Mayulu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Nutrition
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Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.939073/full