Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis.

Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis.

MicroRNAs (miRNAs) are recognized as important regulators of cardiac development, hypertrophy and fibrosis. Recent studies have demonstrated that genetic variations which cause alterations in miRNA:target interactions can lead to disease. We hypothesized that genetic variations in miRNAs that regula...

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Bibliographic Details
Main Authors: Xiaoping Lin, Steven Steinberg, Suresh K Kandasamy, Junaid Afzal, Blaid Mbiyangandu, Susan E Liao, Yufan Guan, Celia P Corona-Villalobos, Scot J Matkovich, Neal Epstein, Dotti Tripodi, Zhaoxia Huo, Garry Cutting, Theodore P Abraham, Ryuya Fukunaga, M Roselle Abraham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0156065&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0156065&type=printable

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