Reactive oxygen species induce Cox‐2 expression via TAK1 activation in synovial fibroblast cells

Reactive oxygen species induce Cox‐2 expression via TAK1 activation in synovial fibroblast cells

Oxidative stress within the arthritis joint has been indicated to be involved in generating mediators for tissue degeneration and inflammation. COX‐2 is a mediator in inflammatory action, pain and some catabolic reactions in inflamed tissues. Here, we demonstrated a direct relationship between oxida...

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Bibliographic Details
Main Authors: Yuta Onodera, Takeshi Teramura, Toshiyuki Takehara, Kanae Shigi, Kanji Fukuda
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:FEBS Open Bio
Subjects:
Reactive oxygen species
Cox-2
TAK1
Synovial tissues
OA model
Online Access:https://doi.org/10.1016/j.fob.2015.06.001

Internet

https://doi.org/10.1016/j.fob.2015.06.001

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