Radiolabeling and Preliminary In Vivo Evaluation of the Candidate CCR2 Targeting PET Radioligand [<sup>11</sup>C]AZD2423
Background: AZD2423 is a high-affinity and selective negative allosteric modulator of the chemokine receptor type 2 (CCR2). This receptor plays important roles in the extravasation and transmigration of monocytes under inflammatory conditions. The aims of the current positron emission tomography (PE...
| Main Authors: | , , , , , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
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MDPI AG
2025-01-01
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| 丛编: | Pharmaceuticals |
| 主题: | |
| 在线阅读: | https://www.mdpi.com/1424-8247/18/2/135 |