Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX

Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX

A series of carboxamide derivatives of 6- and 7-substituted coumarins have been prepared by an original procedure starting from the corresponding 6- or 7-hydroxycoumarins which were alkylated with ethyl iodoacetate, and the obtained ester was converted to the corresponding carboxylic acids which wer...

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Bibliographic Details
Main Authors: Aikaterini Peperidou, Silvia Bua, Murat Bozdag, Dimitra Hadjipavlou-Litina, Claudiu T. Supuran
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Molecules
Subjects:
coumarins
carboxamides
carbonic anhydrase
lipoxygenase
enzyme inhibitor
Online Access:http://www.mdpi.com/1420-3049/23/1/153

Internet

http://www.mdpi.com/1420-3049/23/1/153

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