A novel, high throughput, and low-cost method for the detection of 40 amines relevant to inborn errors of metabolism, in under 60 min, using reverse phase high performance liquid chromatography

Objectives: An assessment of amino acid and amine concentrations is important for the diagnosis and management of inherited metabolic disorders (IMDs). Methods exist that measure these biologically important metabolites but are cost-prohibitive and/or time consuming. We therefore sought to develop a...

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Váldodahkkit: Kirkland A. Wilson, Yun Zhou, Gary Cunningham, Kimberly Chapman, Marshall Summar, Debra Regier
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Elsevier 2025-06-01
Ráidu:Molecular Genetics and Metabolism Reports
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Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2214426925000175