Multi-species atlas resolves an axolotl limb development and regeneration paradox

Abstract Humans and other tetrapods are considered to require apical-ectodermal-ridge (AER) cells for limb development, and AER-like cells are suggested to be re-formed to initiate limb regeneration. Paradoxically, the presence of AER in the axolotl, a primary model organism for regeneration, remain...

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Bibliographic Details
Main Authors: Jixing Zhong, Rita Aires, Georgios Tsissios, Evangelia Skoufa, Kerstin Brandt, Tatiana Sandoval-Guzmán, Can Aztekin
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41944-w