Muscarinic receptor M3 activation promotes fibrocytes contraction

Muscarinic receptor M3 activation promotes fibrocytes contraction

Fibrocytes are monocyte-derived cells able to differentiate into myofibroblasts-like cells. We have previously shown that they are increased in the bronchi of Chronic Obstructive Pulmonary Disease (COPD) patients and associated to worse lung function. COPD is characterized by irreversible airflow ob...

Full description

Bibliographic Details
Main Authors: Pauline Henrot, Edmée Eyraud, Elise Maurat, Sophie Point, Guillaume Cardouat, Jean-François Quignard, Pauline Esteves, Thomas Trian, Pierre-Olivier Girodet, Roger Marthan, Maéva Zysman, Patrick Berger, Isabelle Dupin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
fibrocyte
COPD
M3
cholinergic
contraction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.939780/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.939780/full

Similar Items