Pemetrexed Hinders Translation Inhibition upon Low Glucose in Non-Small Cell Lung Cancer Cells

Pemetrexed Hinders Translation Inhibition upon Low Glucose in Non-Small Cell Lung Cancer Cells

Genetic alterations in non-small cell lung cancers (NSCLC) stimulate the generation of energy and biomass to promote tumor development. However, the efficacy of the translation process is finely regulated by stress sensors, themselves often controlled by nutrient availability and chemotoxic agents....

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Bibliographic Details
Main Authors: Marie Piecyk, Mouna Triki, Pierre-Alexandre Laval, Helena Dragic, Laura Cussonneau, Joelle Fauvre, Cédric Duret, Nicolas Aznar, Toufic Renno, Serge N. Manié, Cédric Chaveroux, Carole Ferraro-Peyret
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Metabolites
Subjects:
protein synthesis
pemetrexed
glucose availability
ER stress signaling
NSCLC
Online Access:https://www.mdpi.com/2218-1989/11/4/198

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https://www.mdpi.com/2218-1989/11/4/198

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