Intermittent Exposure of Hypercapnia Suppresses Allograft Rejection via Induction of Treg Differentiation and Inhibition of Neutrophil Accumulation

Intermittent Exposure of Hypercapnia Suppresses Allograft Rejection via Induction of Treg Differentiation and Inhibition of Neutrophil Accumulation

Background: In the management of major burn wounds, allogeneic skin transplantation is a critical procedure to improve wound repair. Our previous works found that intermittent exposure to carbon dioxide leads to permissive hypercapnia (HCA) and prolongs skin allograft survival. However, the modulato...

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Bibliographic Details
Main Authors: Yuan-Sheng Tzeng, Yi-Jen Peng, Shih-En Tang, Kun-Lun Huang, Shi-Jye Chu, Shu-Yu Wu, Chia-Pi Cheng
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomedicines
Subjects:
allogeneic skin graft
skin rejection
carbon dioxide
hypercapnia
regulatory T cells
Online Access:https://www.mdpi.com/2227-9059/10/4/836

Internet

https://www.mdpi.com/2227-9059/10/4/836

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