Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosis through Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes

Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosis through Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes

Phloroglucinol (PG) is a component of phlorotannins, which are abundant in marine brown alga species. Recent studies have shown that PG is beneficial in protecting cells from oxidative stress. In this study, we evaluated the protective efficacy of PG in HaCaT human skin keratinocytes stimulated with...

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Bibliographic Details
Main Authors: Cheol Park, Hee-Jae Cha, Su Hyun Hong, Gi-Young Kim, Suhkmann Kim, Heui-Soo Kim, Byung Woo Kim, You-Jin Jeon, Yung Hyun Choi
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Marine Drugs
Subjects:
phloroglucinol
keratinocytes
oxidative stress
ROS
Nrf2/HO-1
Online Access:https://www.mdpi.com/1660-3397/17/4/225

Internet

https://www.mdpi.com/1660-3397/17/4/225

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