Human umbilical cord mesenchymal stem cells ameliorate colon inflammation via modulation of gut microbiota-SCFAs-immune axis

Human umbilical cord mesenchymal stem cells ameliorate colon inflammation via modulation of gut microbiota-SCFAs-immune axis

Abstract Background Inflammatory bowel disease (IBD) is a global health problem in which gut microbiota dysbiosis plays a pivotal pathogenic role. Mesenchymal stem cells (MSCs) therapy has emerged as a prospective novel tool for managing IBD, and which can also regulate the composition of gut microb...

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Bibliographic Details
Main Authors: Airu Liu, Xiaonan Liang, Wenxin Wang, Chen Wang, Jia Song, Jinbo Guo, Donglei Sun, Dong Wang, Mei Song, Jiaming Qian, Xiaolan Zhang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells (MSCs)
Colitis
Gut microbiota
Short-chain fatty acids (SCFAs)
CD4+T homeostasis
Online Access:https://doi.org/10.1186/s13287-023-03471-9

Internet

https://doi.org/10.1186/s13287-023-03471-9

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