Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes.

Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes.

Plasmodium vivax malaria is much less common in Africa than the rest of the world because the parasite relies primarily on the Duffy antigen/chemokine receptor (DARC) to invade human erythrocytes, and the majority of Africans are Duffy negative. Recently, there has been a dramatic increase in the re...

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Bibliographic Details
Main Authors: Anthony Ford, Daniel Kepple, Beka Raya Abagero, Jordan Connors, Richard Pearson, Sarah Auburn, Sisay Getachew, Colby Ford, Karthigayan Gunalan, Louis H Miller, Daniel A Janies, Julian C Rayner, Guiyun Yan, Delenasaw Yewhalaw, Eugenia Lo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008234

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https://doi.org/10.1371/journal.pntd.0008234

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