Swinhoeic acid from Potentilla fragarioides ameliorates high glucose-induced oxidative stress and accumulation of ECM in mesangial cells via Keap1-dependent activation of Nrf2
Objectives Diabetic nephropathy (DN) is one of the most common microvascular complications of diabetes mellitus. Oxidative stress resulting from high glucose promotes accumulation of ECM and development of DN. Activation of Nrf2 could attenuate oxidative stress and following accumulation of ECM. To...
Main Authors: | Huankai Yao, Min Kong, Dan Du, Fengwei Ai, Jindong Li, Yan Li |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2022-12-01
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Series: | Redox Report |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/13510002.2022.2134755 |
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