Glitazone Treatment Rescues Phenotypic Deficits in a Fly Model of Gaucher/Parkinson’s Disease

Glitazone Treatment Rescues Phenotypic Deficits in a Fly Model of Gaucher/Parkinson’s Disease

Parkinson’s Disease (PD) is the most common movement disorder, and the strongest genetic risk factor for PD is mutations in the glucocerebrosidase gene (<i>GBA</i>). Mutations in <i>GBA</i> also lead to the development of Gaucher Disease (GD), the most common type of lysosoma...

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Bibliographic Details
Main Authors: Oluwanifemi Shola-Dare, Shelby Bailess, Carlos C. Flores, William M. Vanderheyden, Jason R. Gerstner
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
neurodegeneration
autophagy
Lewy body
dementia
p62
β-acid glucosidase 1
Online Access:https://www.mdpi.com/1422-0067/22/23/12740

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https://www.mdpi.com/1422-0067/22/23/12740

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