Cytolytic activity score as a biomarker for antitumor immunity and clinical outcome in patients with gastric cancer

Cytolytic activity score as a biomarker for antitumor immunity and clinical outcome in patients with gastric cancer

Abstract Background A simple measure of immune cytolytic activity (CYT) base on mRNA expression levels of two genes, GZMA and PRF1, was recently reported. Here, we aimed to evaluate the CYT score's potential as a measure of antitumor immunity and predictor of clinical outcome in gastric cancer...

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Bibliographic Details
Main Authors: Qingjiang Hu, Kentaro Nonaka, Hiroaki Wakiyama, Yu Miyashita, Yoshiaki Fujimoto, Tomoko Jogo, Kentaro Hokonohara, Ryota Nakanishi, Yuichi Hisamatsu, Koji Ando, Yasue Kimura, Takaaki Masuda, Eiji Oki, Koshi Mimori, Yoshinao Oda, Masaki Mori
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Cancer Medicine
Subjects:
biomarkers
gastric cancer
genomics
immunology
TCGA
Online Access:https://doi.org/10.1002/cam4.3828

Internet

https://doi.org/10.1002/cam4.3828

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