STK11 mutation impacts CD1E expression to regulate the differentiation of macrophages in lung adenocarcinoma

STK11 mutation impacts CD1E expression to regulate the differentiation of macrophages in lung adenocarcinoma

Abstract Background The deficiency of serine/threonine protein kinase 11 (STK11), one of the most common tumor suppressor genes in non‐small‐cell lung cancer, is a crucial player in tumor immune microenvironment regulation. This study attempted to unveil how mutated STK11 impact the differentiation...

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Bibliographic Details
Main Authors: Qingfeng Zhang, Juan Feng, Kui Liu, Xiaoyan Yang, Yun Huang, Bo Tang
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Immunity, Inflammation and Disease
Subjects:
CD1E
lung adenocarcinoma
macrophages
proliferation
STK11 mutation
Online Access:https://doi.org/10.1002/iid3.958

Internet

https://doi.org/10.1002/iid3.958

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