Flipping Back of Extrahelical Guanine after Methyl Repair

Methylation at O6 atom of guanine is a type of DNA damage which can cause a cancer. This damage at O6 atom of guanine in a DNA can be transferred to SG atom of cysteine in O6-alkylguanine-DNA alkyltransferase (AGT). Flipping out of methylated guanine from its base stack is essential to give off the...

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Bibliographic Details
Main Authors: Rajendra Prasad Koirala, Narayan Prasad Adhikari
Format: Article
Language:English
Published: Department of Physics, Mahendra Morang Adarsh Multiple Campus, Tribhuvan University 2022-07-01
Series:Bibechana
Subjects:
Online Access:https://www.nepjol.info/index.php/BIBECHANA/article/view/46430