The process of EDC-NHS cross-linking of reconstituted collagen fibres increases collagen fibrillar order and alignment
We describe the production of collagen fibre bundles through a multi-strand, semi-continuous extrusion process. Cross-linking using an EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide), NHS (N-hydroxysuccinimide) combination was considered. Atomic Force Microscopy and Raman spectroscopy focused on...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2015-01-01
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Series: | APL Materials |
Online Access: | http://dx.doi.org/10.1063/1.4900887 |