Structural Investigation of Therapeutic Antibodies Using Hydroxyl Radical Protein Footprinting Methods

Commercial monoclonal antibodies are growing and important components of modern therapies against a multitude of human diseases. Well-known high-resolution structural methods such as protein crystallography are often used to characterize antibody structures and to determine paratope and/or epitope b...

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Bibliographic Details
Main Authors: Corie Y. Ralston, Joshua S. Sharp
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/11/4/71