Expression and Display of Glycoengineered Antibodies and Antibody Fragments with an Engineered Yeast Strain

Interactions with cell surface receptors enhance the therapeutic properties of many important antibodies, including the low-affinity Fc γ Receptors (FcγRs). These interactions require proper processing of the immunoglobulin G Fc <i>N</i>-glycan, and eliminating the <i>N</i>-g...

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Bibliographic Details
Main Authors: Anjali Shenoy, Srisaimaneesh Yalamanchili, Alexander R. Davis, Adam W. Barb
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/10/4/38