Methods of blinding in reports of randomized controlled trials assessing pharmacologic treatments: a systematic review.

BACKGROUND: Blinding is a cornerstone of therapeutic evaluation because lack of blinding can bias treatment effect estimates. An inventory of the blinding methods would help trialists conduct high-quality clinical trials and readers appraise the quality of results of published trials. We aimed to sy...

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Bibliographic Details
Main Authors: Isabelle Boutron, Candice Estellat, Lydia Guittet, Agnes Dechartres, David L Sackett, Asbjørn Hróbjartsson, Philippe Ravaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-10-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1626553?pdf=render