The Remarkable Plasticity of Macrophages: A Chance to Fight Cancer

It is well established that tumor-associated macrophages (TAM) found in most advanced tumors have a pro-tumoral role. In this context, TAM limit the activity of tumor-infiltrating lymphocytes (TIL), and a number of mechanisms have been described including a trapping in the stroma, impeding TIL to re...

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Bibliographic Details
Main Authors: Nadège Bercovici, Marion V. Guérin, Alain Trautmann, Emmanuel Donnadieu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01563/full