More rapid blood interferon α2 decline in fatal versus surviving COVID-19 patients

More rapid blood interferon α2 decline in fatal versus surviving COVID-19 patients

BackgroundThe clinical outcome of COVID-19 pneumonia is highly variable. Few biological predictive factors have been identified. Genetic and immunological studies suggest that type 1 interferons (IFN) are essential to control SARS-CoV-2 infection.ObjectiveTo study the link between change in blood IF...

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Bibliographic Details
Main Authors: Candie Joly, Delphine Desjardins, Raphael Porcher, Hélène Péré, Thomas Bruneau, Qian Zhang, Paul Bastard, Aurélie Cobat, Léa Resmini, Olivia Lenoir, Laurent Savale, Camille Lécuroux, Céline Verstuyft, Anne-Marie Roque-Afonso, David Veyer, Gabriel Baron, Matthieu Resche-Rigon, Philippe Ravaud, Jean-Laurent Casanova, Roger Le Grand, Olivier Hermine, Pierre-Louis Tharaux, Xavier Mariette
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
COVID-19
pneumonia
SARS-CoV-2
type I interferon
prospective study
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1250214/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1250214/full

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