Protein kinase C inhibitor chelerythrine selectively inhibits proliferation of triple-negative breast cancer cells

Abstract Triple-negative breast cancer (TNBC) is a subtype of breast cancer lacking targeted therapy currently. Recent studies imply that protein kinase C may play important roles in TNBC development and could be a specific target. In this study, we evaluated the anti-proliferative activity of PKC i...

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Bibliographic Details
Main Authors: Wanjun Lin, Jiajun Huang, Zhongwen Yuan, Senling Feng, Ying Xie, Wenzhe Ma
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02222-0